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For example, the largest STEP trial published to date reported that GI issues affected 74.2% of volunteers taking semaglutide, as opposed to 47.9% taking placebo
Cortex 25 , 24402455 (2015)
It shares 94 percent amino acid homology with native human GLP-1, but includes structural modifications that extend its half-life to roughly seven days
Unreconstituted powder: Sealed lyophilized vials can handle room temperature for up to 24 months in most formulations
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