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Conversely, elongating the palmitoyl chain (C16:0) did not substantially alter EC 50
Early receptor and endocrine findings, limited human pharmacology studies, and one proof-of-concept clinical program do not establish an approved indication, general safety, or effectiveness
NeuroReport 23 , 425429 (2012)
Inflammation management
Pharmacological inhibition of the tricarboxylate transporter in the mitochondrial outer membrane inhibits GSIS in INS-1 832/13 cells, indicating that the export of citrate from mitochondria to cytosol is crucial for downstream metabolic pathways [43]
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