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Furthermore, novel formulations of intra-articular therapeutics, such as glucosinolates and enhanced hyaluronic acid, are being explored for their potential to provide both analgesic and structural benefits ( FIGURE 5 Artificial intelligence (AI) and digital health technologies are increasingly being integrated into OA care

doi: 10.1080/1028415X.2023.2244260 10

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Turner (2009, Nat Rev Immunol ) demonstrated how barrier dysfunction increases inflammatory signaling