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A 2025 Institute for Clinical and Economic Review (ICER) report notes that weekly GLP-1s like semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) have become more cost-effective over time due to price reductions and proven long-term benefits ( [11] )

Although survival in patients with compensated cirrhosis is relatively high (90% at 5 years after diagnosis), occurrence of complications worsen this scenario to 30% at 3 years[210, 211]

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Although results vary among patients, most individuals can expect to see these enhancements last for half a year