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Months 6 to 12: The SURMOUNT-5 trial published in the NEJM in 2025 found tirzepatide produced 20.2% body weight loss compared to 13.7% for semaglutide over 72 weeks in patients with obesity

Approximately 85 percent of patients report that side effects are mild, temporary, and manageable with support

Food: Can be administered with or without food

Lipid profile: Measured every 6 to 12 months to monitor changes in cholesterol and triglycerides, since weight loss and metabolic changes can affect these values

[83] Each Miniquick device is designed for single use only and should be discarded appropriately after administration

Replicationindependent chromatin loading of Dnmt1 during G2 and M phases