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Women of childbearing potential should use effective contraception while taking tirzepatide and discuss with their healthcare provider if planning pregnancy, as the medication should be discontinued at least 2 months before a planned pregnancy
Knowing your starting point allows your provider to monitor for hypoglycemia if you take other glucose-lowering medications and to track improvements in insulin resistance throughout treatment
The Novo Nordisk prescribing information explicitly permits this approach: "delay dose escalation for 4 weeks if the patient does not tolerate the escalation dose" [6]
Sources United States Pharmacopeia
Lifestyle intervention in gastroesophageal reflux disease
These reactions are usually mild and self-limiting, but they can be concerning for people who are new to injectable medications
