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Additionally, mitochondrial dysfunction in spermmanifested as decreased mitochondrial MMPimpairs energy metabolism and reduces motility [9, 11]
The Sustained Effects of a Dual GIP/GLP-1 Receptor Agonist, NNC0090-2746, in Patients with Type 2 Diabetes
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Liraglutide 3.0 mg reduced BMI by 4.3% over 56 weeks in adolescents with obesity, while placebo reduced BMI by 0.3% in the long term [115]
However, those who combined discontinuation with intensive lifestyle support (dietitian counseling, exercise programs, behavioral therapy) maintained 7080% of their weight loss
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