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Pentoxifylline attenuates TNF- protein levels and brain edema following temporary focal cerebral ischemia in rats

These findings provide new insights regarding the safety of fluoxetine use during pregnancy and suggest that they may affect embryonic development through an unconventional mechanism

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3.2.4 Developmental and drug-induced microbiome disruption Disruptions to the gut microbiome during early development or the initial phases of psychiatric illness may influence the trajectory of mental disorders (Lavebratt et al., 2019) reported that early-life antibiotic exposure is linked to modestly increased risks for several childhood psychiatric disorders, including mood disorders, suggesting sensitive developmental windows for microbiome perturbations (Lavebratt et al., 2019)

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