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p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
ChaC1 and ChaC2 use the -amine of L-glutamyl residues to cleave the amide bond by transamination, releasing it as a cyclic 5-oxo-l-proline and cysteine glycine dipeptide
doi: 10.1038/bjc.1987.223 75 YoonHLeeS
Further, it may stimulate angiogenesis by interacting with cell surface ATP synthase enzymes [23, 26]
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