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GLP-1 is a hormone released by cells in the small intestine and colon in response to food intake
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Quick Take (TLDR) Mostly animal and in vitro data plus multiple very small uncontrolled human reports (knee pain case series n=16, interstitial cystitis pilot n=12, 2subject IV infusion) and no randomized controlled trials or published human pharmacokinetic profiles
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"When you think about normalizing obesity and the treatment of it, people are used to taking a pill for hypertension or for high cholesterol, so here's another way that it just normalizes it to take a pill for a condition that we know is a chronic disease," Narula said