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Mice lacking a functional SELENOF were found to develop nuclear cataract (lens opacification) at a very early age suggesting that SELENOF may be critical to the quality control system of protein folding in the lens (33)

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Additionally, it has been recommended to shorten follow-up periods for patients using a GLP-1 agonist for more frequent screenings (6 to 12 weeks), especially if DR is present or the patient reports vision loss since their last visit