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In RA, synovial macrophages and T cells excessively secrete TNF-, driving synovial hyperplasia and inducing IL-6 and IL-1 release, which forms an inflammatory amplification loop and leads to cartilage and bone destruction (66)

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Curcumin (Turmeric) Pros: Antioxidant Power: Supports glutathione enzyme activity and restores glutathione levels

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Patients experiencing significant weight loss on tirzepatide who want tissue remodeling support

doi:10.1016/S0021-9258(18)33050-3