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( h ) BRCA1 mRNA expression (n = 3

Clinical trials show semaglutide reduces systolic blood pressure by around 3.5-5 mmHg compared to placebo, likely due to weight loss and direct metabolic effects

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A trial published in The New England Journal of Medicine (2023) demonstrated mean weight reductions of up to approximately 24% of body weight over 48 weeks in adults with obesity a potentially significant finding if confirmed in Phase 3 trials