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Improves insulin resistance in older individuals As people age, they produce less glutathione

329,330 In degenerative joint diseases like OA, the metabolic balance of chondrocytes is disrupted, leading to the overproduction of degrading enzymes and inflammatory mediators, including iNOS, MMP-13, and ADAMTS5 (a disintegrin and metalloproteinase with thrombospondin motifs 5), which participate in cartilage degradation and inflammatory processes

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Safety and monitoring considerations for research applications include assessment of potential effects on tissue regeneration, immune function, and wound healing capacity, as senescent cells may play beneficial roles in some biological processes