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Avoid crushing or chewing the tablet

In MASH (metabolic dysfunction-associated steatohepatitis, formerly NASH), semaglutide 2.4 mg showed significant resolution of steatohepatitis in a proportion of patients

A well-known example is that Nature published an article providing support for the microbiota variation associated with the oral antidiabetic drug metformin in 2015

There is no strong evidence showing higher depression risk compared to other weight loss drugs

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GLP-1Rs are expressed in the pancreas, stomach, intestines, heart, kidneys, lungs as well as multiple regions of the brain [27,28,29]