Ensure the skin is fully dry before injection
As the blood glucose level approaches normal, the amounts of insulin released and glucagon suppressed diminishes, thus tending to prevent an "overshoot" and subsequent low blood sugar (hypoglycemia), which is seen with some other oral hypoglycemic agents
British Journal of Pharmacology (2022) 11
Preclinical studies indicate GLP-1 receptors may be expressed on various immune cells, including macrophages, monocytes, and lymphocytes, though human data remains limited
PIONEER 6 PIONEER 6 was a randomized, double-blind, placebo-controlled trial comparing oral semaglutide to placebo designed to rule out an excess in cardiovascular risk with oral semaglutide among patients with T2DM
PubMed Blonde, L., Umpierrez, G.E., Reddy, S.S., McGill, J.B., Berga, S.L., Bush, M., et al