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After reconstitution, refrigerate the vial at 28 C, protect it from light, use it within a few weeks, and never freeze a mixed vial the full detail is in the storage guide
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Marx W, Teleni L, Opie RS, Kelly J, Marshall S, Itsiopoulos C, et al
PloS One (2014) 9(6):e99835
Also, if you regularly use a retinoid, alternate usage of the tworetinol one night, kojic acid on the other
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