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The mechanisms are mainly focused on appetite restriction and food intake reduction by turning up the satiation signals and turning down the hunger signals in the arcuate nucleus of the hypothalamus (16, 17)
Clinical studies show patients on GLP-1 therapy primarily reduce calories through smaller portion sizes and decreased snacking rather than meal skipping
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shows the percent change in VAT from baseline (Week 0) over time until 52 weeks in completer patients
Inadequate dosing, often done to preserve natural movement, may unintentionally reduce duration
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