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A 2020 pharmacokinetic review in Drug Delivery found that needle length and gauge directly influence the depth of the bolus, which affects absorption rate for small synthetic peptides with molecular weights below 5,000 Da (PubMed overview of SQ absorption)

PMID: 15664732

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Following oral administration of recombinant salmonellae, the seroconversion rate to anti-HBc in mice differed by salmonella strain