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In subjects with T2D, once-daily dosing of 40 mg oral semaglutide for 10 weeks led to an HbA 1c reduction of 1.5% points and a body weight reduction of 5.4 kg relative to placebo treatment

These results suggest a conserved function of TRIM37 in germ cell development in both mice and humans

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Optimization of peptide stability and delivery in preclinical studies