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The partitioning rate in buffer can be considered a measure of the drug's absolute affinity for the RBC-binding sites, while the partitioning rate in plasma indicates the relative drugs affinity for RBC-binding sites with respect to that of the plasma, such as albumin ( i.e., drug molecules that are not bound to albumin or other plasma-binding sites) can partition into RBCs

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Moreover, ATF4 knockdown in T315I-Bcr-Abl cells also slowed down DNA replication fork progression (Fig

Figure 4 4.2.1 Mechanisms of neuronal ferroptosis after intracerebral hemorrhage Due to the presence of the bloodbrain barrier (BBB), iron entry into the brain is tightly regulated