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Finally, a four-year, multicenter, clinical trial in 421 diabetic patients with distal symmetric sensorimotor polyneuropathy found no difference between oral administration of 600 mg/day of lipoic and placebo on the primary endpoint, a composite score that assessed neuropathic impairment of the lower limbs and nerve conduction (78)

CNS Penetrant: Crosses the blood-brain barrier in preclinical models

Diarrhoea (runny poo)

It supports detoxification, improves skin clarity, boosts immunity, reduces inflammation, and enhances cellular energy production

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These symptoms typically resolve as the body adapts to increased glutathione levels