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fumigatus gliZ were alive at 24 h and the wild-type strain exhibited greater virulence than gliZ (60% (12/20) versus 20% (4/20) mortality, respectively), at 48 h post-inoculation, thereby confirming the utility of the model system for detection of alteration in virulence associated with gliotoxin production

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The exogenous sources of Cys are through the direct absorption of Cys by excitatory amino acid transporter 3 (EAAT3) and alanine/serine/cysteine/threonine transporter 1, or through the intake of cystine via SLC7A11 and SLC3A2, which is then converted to Cys in the cytoplasm through the catalyzation of glutamate-cysteine ligase (GCL)

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