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The two main culprits here are cortisol (the primary stress hormone) and prolactin

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In practice, that same additive quality is also the main risk: two strong satiety agents together can suppress appetite and slow the gut more than intended, which is why tolerability not maximum weight effect tends to be the limiting factor in any amylin-plus-incretin discussion

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Besides, our study was neither randomized nor blinded, leading to potential bias, whose influence should be mitigated by matching for relevant confounders

This provides ample nutritional support for tissue repair