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Several RCTs including SAVORTIMI 53 (saxagliptin) [52], EXAMINE (alogliptin) [53], and TECOS (sitagliptin) [54] have shown that DPP4 inhibitors did not significantly reduce stroke risk [1]

Second, although this analysis included 45 studies with a fairly large sample size, the low incidence of thyroid events resulted in a wide confidence interval that reduced the certainty of our findings

They make it seem as though you can kind of take all of this into your own hands without any supervision, and that can have some very harmful consequences, Glowacki says

Others are being oversold

16 , with the following modifications

Subcutaneous Self-Injection (Most Common Route) Typical injection sites: Abdomen Thigh Flank Providers should be trained in: Site rotation Sterile technique Dose measurement Safe needle disposal 2