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In order to avoid dryness or irritation, be sure to leave 3-4 days in between exfoliating treatments

A 2025 meta-analysis of randomized trials found small-to-moderate improvements in attention and task switching

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Postmortem studies of PD brains have demonstrated microglial activation in the substantia nigra pars compacta (SNpc), characterized by increased expression of markers such as HLA-DR, CD68, and Iba-1, along with elevated production of pro-inflammatory mediators including IL-1, TNF-, IL-6, and reactive oxygen species (ROS) [73]