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Asian J Pharm Res

doi: 10.3389/fimmu.2023.1160116 93 LiuP-SChenY-TLiXHsuehP-CTzengS-FChenHet al

Other studies collectively illustrated that the dysregulated gene expression of IGF1, IGF2, SMAD3, CXCR1, ACP5, CEACAM3, S1PR4, and TCF7 matched PCOS disease risk by the nomogram, spurring the dysregulation of ovarian biological processes (regarding transporter activity, catalytic activity, tyrosine phosphorylation of STAT5 protein, and immune response) [44,45,46]

Lowering protein by an average of 0.72 grams per kilogram of body weight per day resulted in an average decrease of 25% in IGF-1 (30)

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