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Clinical trial studies regarding the effect of -LA supplementation on migraine were limited, and the existing studies prescribed different therapeutic doses without examining the serum level of -LA
NICE guidelines (NG28) recommend specific injectable GLP-1 receptor agonists for type 2 diabetes management in appropriate clinical contexts
Changes in thyroid function tests are generally not observed, despite theoretical concerns based on animal studies showing thyroid C-cell effects
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Good test-retest reliability was found for the ISI between Week 4 and 12 (ICC 0.819)
STEP and SELECT Trial Data, What Researchers Are Working From The pivotal STEP 1 trial (Wilding et al., NEJM 2021, NCT03548935) enrolled 1,961 adults with obesity (no T2D) over 68 weeks at the 2.4mg/week dose
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