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The S-thiolating activity of membrane g-glutamyltransferase: formation of cysteinyl-glycine mixed disulfides with cellular proteins and in the cell microenvironment

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Additionally, patients taking immunosuppressive medications may have altered responses to infections, and any medication causing significant gastrointestinal symptoms could affect absorption of oral immunosuppressants

Nov 2008;14(6):519-24

They are a visible marker of cumulative UV damage to the lip tissue