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Biomed Pharmacol J
Beyond 6 months , ongoing maintenance therapy prevents recurrence of deficiency
For instance, the durian cultivar Puangmanee (PM) exhibits the highest resistance to Phytophthora palmivora , likely owing to the high expression of genes encoding chitin response proteins, RUN1, RPV1, and RGA4, compared with two susceptible cultivars [Monthong (MT) and Kradumthong (KD)] (Nawae et al
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Eryptosis and aging Multicellular organisms are subject to the biological process of aging, and recently 12 different hallmarks of aging have been defined: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, dysregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis [415]
Combined research protocols allow investigators to examine whether modulating NAD+ availability alongside mitochondrial redox activity produces measurable effects on cellular energy metabolism endpoints
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