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Cold temperatures slam the brakes on these molecular interactions, preserving the peptides integrity for the long haul

Nitric oxide pathway modulation: The peptide interacts with the nitric oxide system, which regulates blood flow and cellular signaling

In Cohort 1, 25 WT and 25 RAMP1/3 KO male mice aged 1220 weeks old were injected intraperitoneally after a 12-hour fast with vehicle, sCT at doses of 3 or 150 nmol/kg, or Cagrilintide at a dose of3 nmol/kg

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The cerebellar cortex appeared to be the most affected, and the cerebral cortex was the least affected

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