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Usage Instructions: Administer as directed by your healthcare provider, typically into the muscle (intramuscularly) for better absorption and effectiveness

Evaluate other medications that may affect heart rate or rhythm, including decongestants, stimulants, thyroid hormone replacement, or medications that prolong the QT interval

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PMCID: PMC9927842 Onyeakazi UM, Columb MO, Rosalind A, Kanakarajan S, Galley HF (2024) Melatonin treatment has consistent but transient beneficial effects on sleep measures and pain in patients with severe chronic pain: the DREAM-CP randomised controlled trial

Metabolic reactions intrinsically generate oxygen radicals, and mitochondria are the major source of metabolic ROS 41