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Some clinical experts and recent Phase 3 reporting have also noted that weight loss in some participants has been substantial enough to raise questions about how much weight loss may be too much, particularly when these medications are used outside tightly controlled medical settings and without provider supervision

Specifically, SGLT2 inhibitors were associated with an increased risk of UTIs compare to non-Asian patients, but the risk of UTI was similar to placebo in Asian patients (56)

10.1073/pnas.2303696120 49 LiQ.TangryV.AllenD

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Analysis of static glucose-stimulated insulin secretion (GSIS) revealed no difference in insulin secretion (Fig

Evaluation of the effect of GLP-1 agonists on quality of bowel preparation for colonoscopy in patients with diabetes