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In terms of body weight reduction, tirzepatide at doses of 15 mg, 10 mg and 5 mg demonstrated greater efficacy than semaglutide at doses of 2.0 mg, 1.0 mg and 0.5 mg, respectively

The mechanism isn't fully mapped, but it likely involves circadian modulation of vagal afferent sensitivity

Understanding the difference between research-grade and pharmaceutical-grade peptides is critical for researchers

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