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Astrocytes Highly specialized star-shaped glial cells located in the brain and spinal cord and involved in several processes, including support of the bloodbrain barrier, provision of nutrients to neurons, repair and scarring following injury, and facilitation of neurotransmission -Amino--carboxymuconate -semialdehyde decarboxylase In de novo NAD + biosynthesis, it is the enzyme that catalyses the decarboxylation of -amino--carboxymuconate -semialdehyde to -aminomuconate -semialdehyde