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Gut microbiota-brain axis in depression: the role of neuroinflammation
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One consistent finding is that peak tissue changes often lag weight loss, with maximal soft-tissue sagging commonly observed 6 to 12 months post-initial weight loss, aligning with clinical guidance that peak GLP-1 weight loss occurs at about 52 weeks
To investigate the cellular basis of these differences, OM and SQ adipose tissues obtained at surgery from obese men and women were placed in organ culture for 7 d with varying concentrations of insulin and dexamethasone
Archives of Gerontology and Geriatrics, 44 , 213-216
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