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Probiotic supplementation has shown mixed results in research, and there is currently insufficient evidence to recommend specific strains for GLP-1 enhancement

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Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes (PIONEER 9): a 52-week, phase 2/3a, randomised, controlled trial

doi: 10.1111/dom.14572 69 MinTBainSC

Clinical use: Supervised protocols at medical clinics involve subcutaneous injection over 4 to 8 weeks, with dosing individualized to injury type and severity