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SGLT-2 inhibitors are widely used to guard against progression of kidney disease in adults with CKD, both with and without type 2 diabetes
Natural products exhibit a diversity of chemical structures as flavonoids, alkaloids, phenolic acids, terpenoidsetc
However, it is essential to acknowledge that competing risks, such as non-CV death during the pandemic, could have influenced the observed effects on CV death rates, as non-CV deaths might have 'competed' with CV deaths as causes of mortality
Approval of the protocol and animal use were obtained from the institutional ethical committee
Common Side Effects Nausea (the most common side effect) Diarrhea Vomiting Constipation Stomach (abdominal) pain Indigestion or burping Serious Side Effects Serious side effects are rare, but its important to know what to look for if they do occur
It sustains adequate redox cell signaling since a physiologic level of oxidative stress is fundamental for controlling life processes via redox signaling, but excessive oxidation causes cell and tissue damage
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