Pascal, J
It is a version of the natural peptide but is cleaved from the 176 to 191 amino acids
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It reduces oxidative stress and inflammation, major contributors to heart disease
Its design pairs two structurally unrelated peptides, TB-500, a synthetic thymosin beta-4 active fragment, and BPC-157, a gastric-origin pentadecapeptide, that operate through fundamentally different cellular mechanisms but converge on tissue-repair and remodeling outcomes
Remarkably, beneficial effects have been observed across this 100-fold range, suggesting a wide therapeutic window where smaller doses remain biologically active