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The discrepancy is too large to be dismissed as a chance finding, suggest the researchers, but could be the result of publication biassome studies might have been prioritized for publication because of the positive nature of their results whereas the unpublished datasets used in this study would not have been affected by any failure to publish null results
10.1111/j.1398-9995.2007.01389.x 10 CarmelR
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Part of that is the biology we've covered in previous articles declining hormones, shifting metabolic efficiency, resistant fat deposits