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Polyphenols Polyphenols are secondary metabolites of plants with antidiabetic effects, whose benefits are related to the stimulation of insulin and GLP-1 secretion, as well as increasing GLP-1 half-life by inhibiting DPP-4 activity [187]
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Acquired carnitine deficiency Hemodialysis and kidney disorders In the kidney, osmolytes including carnitine are crucial since hypertonicity is usual and the kidney must cope with fluctuations of diuresis (increased production of urine) and antidiruesis
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In experimental endocrinology, this dual-agonist blend is used as a tool compound to investigate GH/IGF-1 axis regulation, pituitary signaling and pulsatile growth hormone secretion patterns in in vitro and in vivo research models