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Most studies are rodent models
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Several transition metal ions can catalyze Fenton and Fenton-like reactions to produce hydroxyl radicals (OH) and kill cancer cells in the TME
Gene knockout A gene deletion mutant was constructed from E
Cysteine is frequently identified as rate-limiting, or limiting the ability of glutathione synthesis based on lack of availability
demonstrated that baicalin inhibits airway smooth muscle cell proliferation and airway remodeling-associated gene expression, including IL13, vascular endothelial growth factor, TGF1, matrix metalloproteinases (MMP) 9, and tissue inhibitor of metalloproteinase 1 via the MAPK and RAS signaling pathways, implicating a role in preventing airway remodeling [213]
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