At present, several studies have found that GLP-1 analog Lira may improve lipid metabolism and fat deposition by downregulating the expression of lipid metabolism-related genes FAS, and ACC-a mRNA, or promoting the expression of PI3K protein in mouse liver
Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2022
The body becomes resistant to insulin and can no longer use glucose properly as a fuel, so glucose begins circulating in the bloodstream and may lead to problems with the circulatory, nervous and immune systems
Start once a day, preferably at night
Dose verification and a comprehensive evaluation of contributing factors may be warranted
Lancet (London, England) , 396 , 12231249