Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver
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Future prospective studies should use more extensive fatigue questionnaires, such as the Fatigue Assessment Scale (FAS) (64) or the 11-point fatigue numeric rating scale (NRS) (65, 66)
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Foods to prioritise include: Berries such as blueberries, raspberries, and strawberries Olive oil and oily fish, which contain omega-3 fatty acids Turmeric extract, which contains curcumin Green tea, which is rich in catechins Vitamin C-rich foods such as citrus fruits and peppers Exercise regularly Regular exercise has been shown to boost glutathione production and improve antioxidant defences
In 2018, the recommendations of the international evidence-based guidelines for the assessment and management of PCOS [1] indicated that, although its use is generally off label, metformin can be considered in addition to lifestyle in women with PCOS and Body Mass Index (BMI) 25 kg/m 2 to potentiate weight loss and to improve endocrine and metabolic outcomes