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4.2 Primary ovarian insufficiency Primary ovarian insufficiency (POI), historically referred to as premature ovarian failure (POF), affects 1%3% of women under 40 and arises from accelerated follicular loss or dysfunction (Touraine et al., 2024)

Combination superior: 15-20% vs 5-10% weight loss

Holthe M, Klepstad P, Zahlsen K, Borchgrevink PC, Hagen L, Dale O et al

It persists either in an oxidized state, known as GSSG, or in its most popularly known reduced state, called GSH

Cells were grown to roughly 85% confluence and CSE was diluted in the media to a final concentration of 20%

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