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The absolute risk increase for diabetic retinopathy complications was greater among patients with a history of diabetic retinopathy at baseline (semaglutide 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide 0.7%, placebo 0.4%)

Catching and correcting a confirmed deficiency early is generally simpler and less costly than treating the complications that a long-standing deficiency can cause

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Current treatments and innovations in diabetic retinopathy and diabetic macular edema

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The neuroprotective effects align with BDNF-supporting mechanisms, including reduced hippocampal lipid peroxidation