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Acetylcholine is one of the most important neurotransmitters necessary for memory learning, concentration and muscle movement

In vitamin B12 deficiency, lack of production of the methylating agent, SAM, would lead to a reduced ability to control the effects of histamine in the brain

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According to NICE guidance (NG28 for diabetes

I often advise patients to use a retinol twice a week initially, or in conjunction with a moisturizer to help decrease these effects

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