It is frustrating to us as Patient Advocates that initial evidence relied on was not at that time suitably researched or understood and now, 30 years on, of course, we know so much more
P.SwagellC
Proposed mechanisms include: Enhancing cellular communication Supporting local growth factor expression Modulating nitric oxide pathways for circulation While promising, its important to note that human trials remain limited , and more research is needed before drawing definitive conclusions
For reconstitution, a larger 3mL syringe is often easiest for handling volumes of 1-2mL
[1] [6] Severe deficiencies may include symptoms of reduced heart function, suppression of bone marrow, as well as more various severe neurological symptoms possibly including sensory loss, abnormal balance and reflexes, memory and consciousness impairment, smell and taste problems, depression, irritability, confusion, and psychosis
In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop