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All patients initiated injectable semaglutide or tirzepatide for obesity or type 2 diabetes and stopped the medication within three to 12 months

Disadvantage: long-term efficacy beyond 48 weeks still being studied in Phase 3 trials

In addition, combination therapy with ixekizumab (Taltz) is in Phase 3 trials for adults with plaque psoriasis (PSO) or psoriatic arthritis (PsA)

doi: 10.1016/j.pharmthera.2022.108270 42 GoEJHwangS-MJoHRahmanMMParkJLeeJYet al

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[20] [21] These changes lead to reduced appetite, earlier satiety, and metabolic improvements including enhanced insulin sensitivity