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As not all patients with fatty livers develop NASH, some individuals must possess protective mechanisms to shield them from lipotoxicity, e.g., lipid desaturation and inhibition of lipid-induced inflammation [67]

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Instead, neuronal GLP-1Rs located outside the BBB primarily serve as peripheral targets for gut-derived or pharmacologically administered GLP-1 (Varin et al., 2019

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Discuss labs and protocols with a clinician if you have medical conditions or take medications